Increase in superoxide dismutase (SOD) activity

Acetyl Tetrapeptide-5 supports SOD activity, which contributes to the protection of skin cells from oxidative stress. As a result, the peptide helps inhibit the glycation process that leads to the formation of protein cross-links, which in turn improves skin elasticity and prevents premature aging.

Improved microcirculation

By stimulating microcirculation in the eye area, Acetyl Tetrapeptide-5 reduces blood vessel permeability and moisture loss. This action contributes to the reduction of puffiness and dark circles under the eyes, providing a more rested and youthful appearance.

Anti-glycation effect

Glycation is a process in which sugars react with proteins to form advanced glycation end products (AGEs), which damage collagen and elastin, leading to loss of firmness and wrinkles. Acetyl Tetrapeptide-5 effectively inhibits this process, promoting skin structure and elasticity.

Cosmetic benefits

Thanks to its anti-edematous properties, Acetyl Tetrapeptide-5 is particularly effective in reducing bags under the eyes, which are often the result of poor lymphatic circulation and fluid accumulation. This peptide improves lymphatic circulation, which reduces puffiness and provides a more rested appearance. In addition, it has a calming and moisturizing effect on the skin, improving its smoothness and elasticity. The peptide also exhibits anti-inflammatory properties, which helps reduce skin irritation and redness. It is an excellent ingredient in products for sensitive and allergy-prone skin.

Research

The effectiveness of Acetyl Tetrapeptide-5 has been confirmed in numerous in vivo studies. In one study, 20 volunteers used a cream containing Acetyl Tetrapeptide-5 for 60 days. The results showed that in 70% of participants, the visibility of bags under the eyes decreased by the 15th day of use, and in 95% of participants by the end of the study.

Security

The product is considered a safe cosmetic ingredient. It does not show irritant or toxic effects at the concentrations used. Its lack of classification as a hazardous substance under chemical regulations confirms its safety for both users and the environment.

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Thanks to its properties, ergothioneine is effective in protecting the skin from the harmful effects of UV rays, minimizing the formation of reactive oxygen species, which translates into a reduction in radiation damage to the skin. This is especially important in the context of protection against skin aging and DNA damage. Ergothioneine also shows the ability to reduce inflammatory processes and protect water proteins from oxidative damage.

In in vitro studies, ergothioneine has shown high efficacy as an antioxidant, as confirmed by physicochemical tests for its ability to neutralize DPPH free radicals. In experiments on zebrafish, its pronounced antioxidant effects were found.

Ergothioneine is used in a wide range of cosmetic products, including eye serums, creams, gels, providing whitening, dark circles reduction, anti-aging and moisturizing effects. It is a versatile compound that addresses the diverse needs of the skin, protecting it from external and internal factors that cause aging and damage.

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Hexapeptide-2 is used in cosmetic products such as whitening creams, essences, eye creams and face masks. In addition to its skin whitening and brightening effects, the ingredient also promotes collagen production, which translates into anti-aging effects.

In in vitro studies, hexapeptide-2 has shown efficacy in brightening the skin and promoting collagen generation, which is key to improving skin firmness and elasticity.

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In in vitro experiments, nonapeptide-1 has demonstrated the ability to significantly reduce melanin levels and inhibit tyrosinase activity, translating into efficacy in skin brightening and pigmentation spot reduction. It is a substance of high purity (98.0%), produced by biological fermentation, the recommended concentration in products is 0.1-0.2%.

It is mainly used in skin care products aimed at smoothing skin tone, reducing uneven pigmentation and improving overall brightness and evenness of the complexion.

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Acetyl dipeptide-1 cetyl ester mimics the structure of β-endorphin, allowing it to relieve stimulation and inhibit the release of CGPR, thereby reducing the synthesis of inflammatory factors and relieving inflammation and burning sensations in the skin. Its unique lipid structure provides the skin with essential fats, reduces water evaporation and makes the skin soft and radiant. This peptide is able to easily penetrate the stratum corneum and reach the deep layers of the skin to work effectively there.

Application:

Acetyl dipeptide-1 cetyl ester is widely used in cosmetic products, including serums, eye creams, face masks and moisturizers. Its effects include anti-inflammation, anti-sensitization, soothing irritation, regenerating the skin and improving its overall condition.

The recommended concentration of the additive in cosmetic products is between 0.01% and 0.025%. This ingredient is especially recommended for products designed for sensitive, irritated skin and skin in need of intensive regeneration and hydration.

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The use of palmitoyl tripeptide-8 is recommended in a wide range of skin care products, such as gels, lotions, AM/PM creams, eye serums and face masks. This product provides relief from skin irritation, has anti-inflammatory and anti-allergenic effects, and soothes the effects of external stimuli.

The recommended concentration of the additive in cosmetic products is between 0.0005% and 0.01%. Palmitoyl tripeptide-8 is especially recommended for products dedicated to sensitive, irritation-prone skin, as well as for products aimed at alleviating the effects of skin aging.

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Ectoin works at the molecular level by increasing the ability of water molecules to form hydrogen bonds. This creates a hydration layer around the proteins, which protects the skin from moisture loss, strengthens and repairs cellular functions and stabilizes the skin barrier. This action makes Ectoin extremely effective in protecting and regenerating the skin while minimizing the risk of irritation.

In vitro experiment

According to Hunter Biotech’s test report, it was found that the caudal fin area of the fish in the test group that received Ectoin application increased significantly compared to the control group. This result indicates the effectiveness of Ectoin in the repair and regeneration process.

Applications:

Ectoin is used in a wide range of cosmetic products, offering protection, repair, anti-inflammatory, allergy relief, anti-aging and moisturizing effects. It is a key ingredient in products such as day and night creams, essences, eye creams and face masks. Thanks to its properties, Ectoin is an ideal choice for those looking for broad-spectrum active ingredients that effectively care for and protect the skin.

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Palmitoyl tripeptide-7 acts on keratinocytes to reduce the secretion of interleukin-6 (IL6). This helps maintain the skin’s cellular balance and minimize the inflammatory response. Thus, this ingredient effectively improves the firmness and elasticity of the skin. In addition, it acts as a cellular messenger, stimulating the synthesis of collagen (types I, II, IV) and elastin in the skin, which contributes to the regeneration of collagen fibers.

An experiment in anti-aging effectiveness:

In a study involving 28 subjects, palmitoyl tripeptide-7 was applied to the face. The results showed that after a two-month application of the ingredient, there was a significant increase in skin fiber content compared to baseline.

Applications:

Palmitoyl tripeptide-7 is widely used in cosmetic products providing anti-aging, anti-wrinkle, anti-inflammatory, firming, anti-allergic and other effects. It is a key ingredient in products such as gels, lotions, day and night creams, eye serums and face masks.

The recommended concentration for use in products is between 0.002% and 0.01%.

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Hydroxypropyl tetrahydropyrantriol works by stimulating extracellular matrix synthesis. Its effects include inducing the generation of glycosaminoglycans (GAGs) in the epidermis, accelerating the production of type IV and VII collagen by dermis cells, and strengthening the connection between the dermis and epidermis. This ingredient effectively improves epidermal adhesion, which translates into increased skin firmness and elasticity.

Efficacy Experiments:

According to a report by Hunter Biotech, the use of hydroxypropyl tetrahydropyrantriol was found to significantly increase the expression of type I collagen precursor compared to the control group, indicating the anti-aging efficacy of this substance.

Applications:

Hydroxypropyl tetrahydropyrantriol is used in a wide range of cosmetic and personal care products. It is especially recommended for use in products such as day and night face creams, eye serums, as well as in lotions and other moisturizers. Its anti-aging, moisturizing and firming effects make it the ingredient of choice for premium cosmetics manufacturers seeking effective and innovative skin care solutions.

Concentration recommended:

The recommended concentration for the use of hydroxypropyl tetrahydropyrantriol in cosmetic products ranges from 0.1% to 10%, allowing the formulation to be tailored to individual needs and product goals.

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Its action is to stimulate the production of Syndecan-1, which translates into strengthening the bonds between epidermal cells, which can lead to improved firmness and elasticity of the skin. As a result, the skin becomes more resistant to external factors and less susceptible to the aging process. Regular use of products with tetrapeptide-11 can help smooth wrinkles, improve skin texture and increase skin hydration.

This product is recommended for use in low concentrations (0.000105-0.0165%), and its effectiveness has been confirmed in laboratory studies. Acetyl tetrapeptide-11 is safe to use and well tolerated by the skin, making it an ideal ingredient for those seeking effective but gentle anti-aging cosmetic solutions.

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